منابع مشابه
Rational polypharmacy
The development of assays for plasma antiepileptic drug concentrations has led to the discovery of many pharmacokinetic interactions, some causing drug intoxication and others resulting in ineffective drug concentrations. In the 1970s, a number of epileptologists began to argue that single drug therapy was desirable in the treatment of epilepsy and this has become the accepted policy when initi...
متن کاملPolypharmacy vs. Deprescribing
Usually, the elderly and patients with chronic diseases visit several doctors and are supposed to take multiple medications. The multiplicity of medications is called polypharmacy and it may cause side effects, drug interactions and other helth issues for the patient, and it might go as far as the patient might need to go to the hospital and be admitted in ICU, or even further and be the cause ...
متن کاملFall and rise of polypharmacy?
Early in the 20th century, in an era before the wide availability of effective drugs with established dose ranges and proven outcomes, the use of multiple drug combinations in individual tablets and capsules, described as polypharmacy, was common. Although there may have been a rational selection of agents sometimes, on more occasions a mixture was developed of dubious efficacy and rationale. W...
متن کاملConscientious family physicians and polypharmacy.
One of the traditional goals of internist geriatricians and of family physicians providing care for elderly patients has been to review and reduce the amount of medication patients are taking. This can be one of the great pleasures of geriatric medicine, with obvious and proven benefits for older patients. Polypharmacy can be defined as the concomitant use of many medications. The more medicati...
متن کاملUnnecessary polypharmacy for epilepsy.
A retrospective survey of 50 adult epileptic outpatients who were taking two anticonvulsants drugs showed that seizure control had improved in the six months after the introduction of the second drug in only 36%. When blood concentrations of the two anticonvulsants were subsequently measured improvement in seizure control was found to be significantly related to the presence of optimum blood co...
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ژورنال
عنوان ژورنال: Practical Diabetes International
سال: 2004
ISSN: 1357-8170,1528-252X
DOI: 10.1002/pdi.680